Chen-Gounelas-Liedtke recently introduced a powerful regeneration technique, a process opposite to specialization, to prove existence results for rational curves on projective K3 surfaces. In the talk I will present a joint work with G. Mongardi in which we show that, for projective irreducible holomorphic symplectic manifolds, an analogous regeneration principle holds and provides a very flexible tool to prove existence of uniruled divisors, significantly improving known results.