The chiralization in the title denotes a certain procedure which turns cluster X-varieties into q-W algebras. Many important notions from cluster and q-W worlds, such as mutations, global functions, screening operators, R-matrices, etc emerge naturally in this context. In particular, we discover new bosonizations of q-W algebras and establish connections among previously known bosonizations. If time permits, I will discuss potential applications of our approach to the study of 3d topological theories and local systems with affine gauge groups. This talk is based on a joint project with J. Shiraishi, J.E. Bourgine, B. Feigin, A. Shapiro, and G. Schrader. -- This seminar is part of the activities of the Project PRIN 2022S8SSW2 funded by the European Union – Next Generation EU.